Triethyl 2-fluoro-2-phosphonoacetate

Triethyl 2-fluoro-2-phosphonoacetate
What is Triethyl 2-fluoro-2-phosphonoacetate?
Triethyl 2-fluoro-2-phosphonoacetate is a chemical compound with CAS number 2356-16-3. It is used in various industrial and research applications.
Applications
Reactant for:
• Diels-Alder reactions1
• Biosynthesis of terpene2
• Stereoselective synthesis of unsaturated esters, fluorides and nitriles from the reactions of aldehydes and ketones using Wadsworth-Emmons phosphonates3
• Synthesis of quinolones4
• Horner-Wadsworth-Emmons asymmetric hydration5
• Addition reactions and the subsequent application to click chemistry6
• Asymmetric intermolecular Stetter reactions7
Specifications
(C2H5O)2P(O)CH(F)CO2C2H5
242.18 g/mol
96%
75 °C/0.01 mmHg(lit.)
1.194 g/mL at 25 °C(lit.)
Safety Information
GHS07Warning
H315-H319-H335
P261-P305 + P351 + P338
Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
3
