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Chloromethyl chloroformate

Chloromethyl chloroformate chemical structure
CAS Number22128-62-7
FormulaN/A
Mol. Weight128.94 g/mol

What is Chloromethyl chloroformate?

Chloromethyl chloroformate is a chemical compound with CAS number 22128-62-7. It is used in various industrial and research applications.

Applications

Chloromethyl chloroformate was used as key reactant in the synthesis of:
• novel aminocarbonyloxymethyl esters of diclofenac and flufenamic acid1
• highly water-soluble monomethoxypoly(ethyleneglycol) prodrugs of cyclosporin A2
• series of 3-acyloxymethyloxycarbonyl-1-aryl-3-methyltriazenes3

Specifications

Linear Formula

ClCOOCH2Cl

Molecular Weight

128.94 g/mol

Assay/Purity

≥98.0% (GC)

Boiling Point

107-108 °C(lit.)

Density

1.450 g/mL at 20 °C

Safety Information

GHS05GHS05
GHS06GHS06
Signal Word

Danger

Hazard Statements

H314-H331

Precautionary Statements

P261-P280-P305 + P351 + P338-P310

Required PPE

Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

EC Number

244-793-3

WGK Germany

3

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