Ethyl (4-fluorobenzoyl)acetate

Ethyl (4-fluorobenzoyl)acetate
What is Ethyl (4-fluorobenzoyl)acetate?
Ethyl (4-fluorobenzoyl)acetate is a chemical compound with CAS number 1999-00-4. It is used in various industrial and research applications.
Applications
Reactant used as a precursor in:
• Condensation reactions with diamines via C-C bond cleavage for synthesis of benzimidazoles and perimidines1 for possible use as antimalarial treatments2
• Base-promoted domino Michael addition / cyclization / elimination reactions for synthesis of hydroxybenzophenones3
• Oxidative cross-coupling with indoles via dioxygen activation4
• Cyclization of keto esters for synthesis of pyrones5
• Lewis base catalyzed hydrosilylation for synthesis of α-acetoxy β-amino acid derivatives6
• Conia-ene reactions for synthesis of methylenecyclopentane derivatives7
Specifications
FC6H4COCH2CO2C2H5
210.20 g/mol
117-120 °C(lit.)
1.174 g/mL at 25 °C(lit.)
