(3-(Dimethylamino)propyl)triphenylphosphonium bromide

CAS Number18355-96-9
FormulaN/A
Mol. Weight428.34 g/mol
(3-(Dimethylamino)propyl)triphenylphosphonium bromide
What is (3-(Dimethylamino)propyl)triphenylphosphonium bromide?
(3-(Dimethylamino)propyl)triphenylphosphonium bromide is a chemical compound with CAS number 18355-96-9. It is used in various industrial and research applications.
Applications
Reactant for preparation of:
• Topoisomerase I-targeting antitumor agents1
• C15-C21 stereopentad of discodermolide via cleavage of aminoglycosides, double-bond isomerization, and selective hydroxyl group protection2
• Diphenyl amine based sodium channel blockers, effective against hNav1.23
• Reactant for Wittig reaction with benzaldehyde4
Specifications
Linear Formula
(CH3)2NCH2CH2CH2P(C6H5)3(Br)
Molecular Weight
428.34 g/mol
Assay/Purity
98%
Safety Information
GHS07Signal Word
Warning
Hazard Statements
H315-H319-H335
Precautionary Statements
P261-P305 + P351 + P338
Required PPE
dust mask type N95 (US), Eyeshields, Gloves
Melting Point
193-196 °C
WGK Germany
3
