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tert-Butyldimethylsilyl chloride

tert-Butyldimethylsilyl chloride chemical structure
CAS Number18162-48-6
FormulaN/A
Mol. Weight150.72 g/mol

What is tert-Butyldimethylsilyl chloride?

tert-Butyldimethylsilyl chloride is a chemical compound with CAS number 18162-48-6. It is used in various industrial and research applications.

Applications

Versatile protecting reagent for amines, amides, and especially alcohols, among others.1 Can be selectively removed in the presence of a t-BuPh2Si-protected alcohol.2
Used in a preparatrion of isoxazoline N-oxides from α-bromonitroalkanes.3

Specifications

Linear Formula

(CH3)3CSi(CH3)2Cl

Molecular Weight

150.72 g/mol

Assay/Purity

97%

Boiling Point

125 °C(lit.)

Density

0.87 g/mL at 20 °C(lit.)<br/>0.866 g/mL at 25 °C

Safety Information

GHS02GHS02
GHS05GHS05
Signal Word

Danger

Hazard Statements

H228-H314

Precautionary Statements

P210-P280-P305 + P351 + P338-P310

Melting Point

86-89 °C(lit.)

EC Number

242-042-4

WGK Germany

2

Frequently Asked Questions