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1-(Trimethylsilyl)imidazole

1-(Trimethylsilyl)imidazole chemical structure
CAS Number18156-74-6
FormulaC6H12N2Si
Mol. Weight140.26 g/mol

What is 1-(Trimethylsilyl)imidazole?

1-(Trimethylsilyl)imidazole is a chemical compound with CAS number 18156-74-6 and molecular formula C6H12N2Si. It is used in various industrial and research applications.

Applications

1-(Trimethylsilyl)imidazole (TMSI) was used for derivatization of carbohydrates into trimethylsilyl ethers1. It was also used to synthesize polysubstituted chiral spirotetrahydropyrans2 and as silylating reagent for the protection of hydroxyl groups in the presence of amine functionalities.3

Specifications

Molecular Weight

140.26 g/mol

Assay/Purity

≥98.0% (T)
≥98.0%

Boiling Point

93-94 °C/14 mmHg(lit.)

Density

0.957 g/mL at 20 °C<br/>0.956 g/mL at 25 °C(lit.)

Safety Information

GHS02GHS02
GHS07GHS07
Signal Word

Danger

Hazard Statements

H225-H315-H319-H335

Precautionary Statements

P210-P261-P305 + P351 + P338

Required PPE

Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

EC Number

242-040-3

WGK Germany

3

Frequently Asked Questions