(Trimethylsilyl)diazomethane solution
(Trimethylsilyl)diazomethane solution
What is (Trimethylsilyl)diazomethane solution?
(Trimethylsilyl)diazomethane solution is a chemical compound with CAS number 18107-18-1. It is used in various industrial and research applications.
Applications
Reactant for preparation of:
• Macrolactam analogs of the natural product macrolide (-)-A26771B with improved metabolic stability and antibacterial activity1
• Aigialomycin D analogues as protein kinase inhibitors for cancer treatment2
• Unnatural α-amino acid derivatives containing gem-bisphosphonates via Michael addition reaction3
• Capped 4-methylumbelliferyl hyaluronan disaccharides and tetrasaccharides as potential hyaluronidase substrates4
• Stictamides A-C as matrix metallopeptidase 12 (MMP12) inhibitors with antitumor invasion activity5
• Endothelin converting enzyme (ECE) Inhibitors WS 75624A and WS 75624B via a cross-metathesis approach6
• Ent-kaurene derivatives as anti-inflammatory agents7
• Desmosdumotin C analogs as potent antitumor agents acting via activation of spindle assembly checkpo
Specifications
(CH3)3SiCHN2
114.22 g/mol
0.718 g/mL at 25 °C
Safety Information
GHS02
GHS06
GHS08
GHS09Danger
Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
3