(3-Carboxypropyl)triphenylphosphonium bromide
(3-Carboxypropyl)triphenylphosphonium bromide
What is (3-Carboxypropyl)triphenylphosphonium bromide?
(3-Carboxypropyl)triphenylphosphonium bromide is a chemical compound with CAS number 17857-14-6 and molecular formula HO2C(CH2)3P(C6H5)3Br. It is used in various industrial and research applications.
Applications
Reactant for preparation of:
• Piperamide analogs as histone deacetylase (HDAC) inhibitors with antitumor activity1
• Boron-containing benzoxaboroles as antimalarial agents2
• Methyl alkenyl quinolones as antimycobacterial agents3
• Solandelactone E via Sharpless epoxidation, Taber cyclopropanation, chemoselective reductions and lithiation-borylation-all
• Organotin compounds as antifungal agents5
• Oleanolic acid derivatives as inhibitors of protein tyrosine phosphatase 1B for negative regulation of insulin pathway (a promising target for treatment of diabetes and obesity)6
• 11-oxa prostaglandin analogs with ocular hypotensive activity7
Specifications
HO2C(CH2)3P(C6H5)3Br
429.29 g/mol
98%
Safety Information
GHS07Warning
H315-H319-H335
P261-P305 + P351 + P338
dust mask type N95 (US), Eyeshields, Gloves
244-247 °C(lit.)
3