Applications

• Used as a platform for delivery of pro-apoptotic peptides into the mitochondria of tumor cells¹

Reactant for preparation of:
• Ring skeletons via ring closing metathesis and double bond migration ring closing metathesis reactions²
• Methyl alkenyl quinolones as antimycobacterial agents³
• Prostaglandins and their drug analogs via Gold-catalyzed Meyer-Schuster rearrangement⁴
• Diphenylmethylpiperazines as N-type calcium channel blockers as potential therapeutic agents⁵
• Folate receptor-specific glycinamide ribonucleotide formyltransferase (GARFTase) inhibitors with antitumor activity⁶
• Cycloalkylidene alkanols with antileishmanial activity, via Wittig reaction⁷