Tyrphostin AG 1478
CAS Number175178-82-2
FormulaC16H14ClN3O2
Mol. Weight315.75 g/mol
Tyrphostin AG 1478
What is Tyrphostin AG 1478?
Tyrphostin AG 1478 is a chemical compound with CAS number 175178-82-2 and molecular formula C16H14ClN3O2. It is used in various industrial and research applications.
Applications
Tyrphostin AG 1478 has been used as an EGF receptor (EGFR) inhibitor in SW1353 cultures2. AG 1478 is also known to inhibit exogenous TGFα-mediated c-Met phosphorylation in A431 cells3.
Specifications
Molecular Weight
315.75 g/mol
Assay/Purity
≥98%
Solubility
0.1 M HCl: soluble <0.4 mg/mL
DMSO:methanol (1:1): soluble10 mg/mL, clear, colorless
ethanol: soluble10 mg/mL
methylene chloride: soluble10 mg/mL
0.1 M NaOH: insoluble
2-hydroxypropyl-β-cyclodextrin: insoluble
H2O: insoluble