4-Chlorophenylboronic acid
4-Chlorophenylboronic acid
What is 4-Chlorophenylboronic acid?
4-Chlorophenylboronic acid is a chemical compound with CAS number 1679-18-1 and molecular formula ClC6H4B(OH)2. It is used in various industrial and research applications.
Applications
Reagent used for
• Palladium-catalyzed direct arylation1
• Cyclopalladation2
• Tandem-type Pd(II)-catalyzed oxidative Heck reaction and intramolecular C-H amidation3
• Copper-mediated ligandless aerobic fluoroalkylation4
• Pd-catalyzed arylative cyclization5
• Ruthenium catalyzed direct arylation6
• Ligand-free copper-catalyzed coupling reactions7
• Regioselective arylation and alkynylation by Suzuki-Miyaura and Sonogashira cross-coupling reactions8
Reagent used in Preparation of
• Catalysts for Suzuki-Miyaura cross-coupling2
• Palladium(II) thiocarboxamide complexes as Suzuki coupling catalysts9
• Biaryls by Suzuki reactions of aryl chlorides, bromides, and iodides with arylboronic acids10
Specifications
ClC6H4B(OH)2
156.37 g/mol
95%
Safety Information
GHS07Warning
H302 + H312 + H332
P280
dust mask type N95 (US), Eyeshields, Gloves
284-289 °C(lit.)
216-845-5
3