Applications

Reactant for synthesis of:
• Dual substrate-site inhibitors of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase¹
• Unnatural alpha-amino acid derivatives containing gem-biphosphonates²
• Biphenyl sulfonylamino Me bisphosphonic acids as inhibitors of matrix metalloproteinases and bone resorption³
• Lycopene via Wittig-Horner reaction⁴
• Alkylaminoethylbisphosphinic acids to target farnesyl diphosphate synthase⁵
• Aromatic bisphosphonates for use as inhibitors of geranylgeranyl diphosphate synthase⁶

Precursor for synthesis of dendritic polyglycerol anions used toward L-selectin inhibition⁷