Applications

Reagent Used for
• Reductive silylation and the preparation of trifluoro- and difluoromethylsilanes by reductive coupling of fluoromethyl sulfones, sulfoxides and sulfides with chlorosilanes¹
• Fluoroalkylation/chloroalkylation of α,β-enones, arynes, acetylenic ketones and other Michael acceptors²
• Difluoromethylation of primary alkyl halides via nucleophilic substitution-reductive desulfonylation³

Reagent used in Preparation of
• α-difluoromethyl amines via stereoselective (phenylsulfonyl)difluoromethylation of chiral sulfinyl aldimines⁴
• Anti-difluoropropanediols via potassium tert-butoxide-catalyzed difluoromethylenation of aldehydes⁵
• β-difluoromethylated and β-difluoromethylenated alcohols and amines by regioselective nucleophilic difluoromethylation of 1,2-cyclic sulfates and sulfamidates⁶