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ABT-418 hydrochloride

ABT-418 hydrochloride chemical structure
CAS Number147388-83-8
FormulaC9H14N2O · HCl
Mol. Weight202.68 g/mol

What is ABT-418 hydrochloride?

ABT-418 hydrochloride is a chemical compound with CAS number 147388-83-8 and molecular formula C9H14N2O · HCl. It is used in various industrial and research applications.

Applications

ABT-418 [(S)-3-methyl-5-(1 methyl-2-pyrrolidinyl)isoxazole hydrochloride] is a novel neuronal nicotinic acetylcholine receptor (nAChR) ligand with cognitive enhancing and anxiolytic-like activity 3- to 10-fold more potent than (-)-nicotine in rodents. ABT-418 hydrochloride has been used to study new therapeutic approaches for the treatment of Alzheimer’s disease.

Specifications

Molecular Weight

202.68 g/mol

Assay/Purity

≥98% (HPLC)

Solubility

H2O: soluble15 mg/mL

Safety Information

GHS06GHS06
Signal Word

Danger

Hazard Statements

H300-H310-H330

Precautionary Statements

P260-P264-P280-P284-P301 + P310-P302 + P350

WGK Germany

3

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