3-(Trifluoroacetyl)indole

3-(Trifluoroacetyl)indole
What is 3-(Trifluoroacetyl)indole?
3-(Trifluoroacetyl)indole is a chemical compound with CAS number 14618-45-2 and molecular formula C10H6F3NO. It is used in various industrial and research applications.
Applications
• Reactant for enantioselective synthesis of indoles via palladium-catalyzed kinetic asymmetrical alkylation1
• Reactant for preparation of N-pyridinyl indolecarboxamides via amidation of aminopyridine derivatives. with indolecarboxylic acid2
• Reactant for preparation of mast cell tryptase inhibitors, starting from indoles; using amidation as the key step3
• Reactant for formation of Michael adducts via Baylis-Hillman reaction4
• Reactant for preparation of indolecarboxamides via haloform cleavage of (trifluoroacetyl)indole with lithium dialkylamides5
Specifications
213.16 g/mol
99%
Safety Information
GHS07Warning
H315-H319-H335
P261-P305 + P351 + P338
dust mask type N95 (US), Eyeshields, Gloves
211-214 °C(lit.)
3
