Iodoacetamide
Iodoacetamide
What is Iodoacetamide?
Iodoacetamide is a chemical compound with CAS number 144-48-9. It is used in various industrial and research applications.
Applications
Alkylating reagent for cysteine residues in peptide sequencing. By virtue of reaction with cysteine, it is an irreversible inhibitor of enzymes with cysteine at the active site.1 It reacts much more slowly with histidine residues, but that activity is responsible for inhibition of ribonuclease.2
Specifications
ICH2CONH2
184.96 g/mol
Vetec™ reagent grade
≥99% (NMR)
≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter
H2O: soluble0.5 M, clear, colorless
Safety Information
GHS06
GHS08Danger
H301-H317-H334-H413
P261-P280-P301 + P310-P342 + P311
92-95 °C(lit.)
chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%
Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%
205-630-1
3