L-Amethopterin hydrate
CAS Number133073-73-1
FormulaC20H22N8O5 · xH2O
Mol. Weight454.44 (anhydrous basis) g/mol
L-Amethopterin hydrate
What is L-Amethopterin hydrate?
L-Amethopterin hydrate is a chemical compound with CAS number 133073-73-1 and molecular formula C20H22N8O5 · xH2O. It is used in various industrial and research applications.
Applications
Potent inhibitor of dihydrofolate reductase1 and agent for antitumor studies.2,3 Use to inhibit dihydrofolate reductase in DHFR-based protein expression systems. Also effective in treatment of pyrimethamine-resistant Plasmodium vivax malaria parasites.
Specifications
Molecular Weight
454.44 (anhydrous basis) g/mol
Assay/Purity
98%
Solubility
H2O: insoluble
Safety Information
GHS06
GHS08Signal Word
Danger
Hazard Statements
H301-H315-H319-H360
Precautionary Statements
P201-P301 + P310-P305 + P351 + P338-P308 + P313
Required PPE
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
WGK Germany
3