Applications

3-Chloropropyl isocyanate has been used in the preparation of:
• 9,10-dimethoxy- and 9,10-diethoxy-5H-2,3,7,8,12b,13-hexahydroimidazo[1′,2′:3,4]pyrimido[6,1-a]isoquinolin-5-one¹
• 11,12-dimethoxy- and 11,12-diethoxy-2H,6H-3,4,8,9,13b,14-hexahydropyrimido[1′,2′:3,4]pyrimido[6,1-a]isoquinoline-6-one¹
• N-[N′-(3-chloropropyl)-N′-nitrosocarbamoyl]-L-proline²
• 1,3-oxazino[2,3-b]quinazolines via coupling with anthranilamide³