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4-(Trifluoromethyl)phenylboronic acid

4-(Trifluoromethyl)phenylboronic acid chemical structure
CAS Number128796-39-4
FormulaCF3C6H4B(OH)2
Mol. Weight189.93 g/mol

What is 4-(Trifluoromethyl)phenylboronic acid?

4-(Trifluoromethyl)phenylboronic acid is a chemical compound with CAS number 128796-39-4 and molecular formula CF3C6H4B(OH)2. It is used in various industrial and research applications.

Applications

Reagent used for
• Site-selective Suzuki-Miyaura cross-coupling reactions1
• Palladium-catalyzed direct arylation reactions2
• Tandem-type Pd(II)-catalyzed oxidative Heck reaction and intramolecular C-H amidation sequence3
• Ruthenium catalyzed direct arylation4
• Ligand-free copper-catalyzed coupling reactions5
• Amination and conjugate addition reactions6
• Regioselective arylation and alkynylation by Suzuki-Miyaura and Sonogashira cross-coupling reactions7
• Rhodium-catalyzed asymmetric 1,4-addition reactions8
• Copper-catalyzed nitration reactions9
• Regioselective Suzuki-Miyaura coupling and tandem palladium-catalyzed intramolecular aminocarbonylation and annulation10

Reagent used in Preparation of
• Thiazole deriv

Specifications

Linear Formula

CF3C6H4B(OH)2

Molecular Weight

189.93 g/mol

Assay/Purity

≥95.0%

Safety Information

GHS07GHS07
Signal Word

Warning

Hazard Statements

H302

Required PPE

dust mask type N95 (US), Eyeshields, Gloves

Melting Point

245-250 °C(lit.)

WGK Germany

3

Frequently Asked Questions