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Diallyl N,N-diisopropylphosphoramidite

Diallyl N,N-diisopropylphosphoramidite chemical structure
CAS Number126429-21-8
FormulaN/A
Mol. Weight245.30 g/mol

What is Diallyl N,N-diisopropylphosphoramidite?

Diallyl N,N-diisopropylphosphoramidite is a chemical compound with CAS number 126429-21-8. It is used in various industrial and research applications.

Applications

Precursor involved in the synthesis of pharmacologically active molecules including:
• Selective orally active S1P1 agonists1
• Water-soluble prodrugs of triazole CS-758 with antifungal activity2
• Fostriecin analogs as antitumor agents3

Reactant involved in:
• Phosphitylation of alcohols4
• Deallylation for the synthesis of nucleoside phosphoramidite5
• Posphitylation and stereoselective Pudovik rearrangement6

Specifications

Linear Formula

[(CH3)2CH]2NP(OCH2CH=CH2)2

Molecular Weight

245.30 g/mol

Boiling Point

130 °C(lit.)

Density

0.928 g/mL at 25 °C(lit.)

Safety Information

GHS02GHS02
GHS07GHS07
Signal Word

Warning

Hazard Statements

H226-H315-H319-H335

Precautionary Statements

P261-P305 + P351 + P338

Required PPE

Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

WGK Germany

3

Frequently Asked Questions

Alternative Names & Synonyms

[(CH3)2CH]2NP(OCH2CH=CH2)2