Applications

• Chlorosulfonyl isocyanate was used in synthesis and biochemical characterization of new class of membrane-associated glycosyltransferase inhibitors¹.
• It is synthetically versatile reagent² and was used in the preparation of amides³, lactams^4,5 and triazocinones⁶.
• It was employed in regio- and diastereoselective introduction of a protected amino group in synthesis of chiral, polyhydroxylated piperidines⁷.
• It was used as reagent during the synthesis of novel sulfamides⁸.