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7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester

7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester chemical structure
CAS Number113721-87-2
FormulaC16H14N2O6
Mol. Weight330.29 g/mol

What is 7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester?

7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester is a chemical compound with CAS number 113721-87-2 and molecular formula C16H14N2O6. It is used in various industrial and research applications.

Applications

AMCA-NHS has been utilized in the development of a donor europium chelate fluorochrome for use in LRET based analyses by first reacting with an amino group and then with DTPA anhydride 1,2. Utilized in FRET based studies, acting as the donor dye and can be paired with fluorescein-5-isothiocyanate as the acceptor dye 3,4,5. A blue fluorescent dye reactive towards primary amine groups on proteins, peptides, antibodies, and other biomolecules (at pH 7.0-9.0).

Specifications

Molecular Weight

330.29 g/mol

Assay/Purity

≥90% (HPLC)

Solubility

DMF: soluble
DMSO: soluble

Safety Information

GHS07GHS07
Signal Word

Warning

Hazard Statements

H315-H319-H335

Precautionary Statements

P261-P305 + P351 + P338

Required PPE

dust mask type N95 (US), Eyeshields, Gloves

WGK Germany

3

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