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2′-Deoxyuridine 5′-triphosphate sodium salt

2′-Deoxyuridine 5′-triphosphate sodium salt chemical structure
CAS Number102814-08-4
FormulaC9H15N2O14P3 · xNa+
Mol. Weight468.14 (free acid basis) g/mol

What is 2′-Deoxyuridine 5′-triphosphate sodium salt?

2′-Deoxyuridine 5′-triphosphate sodium salt is a chemical compound with CAS number 102814-08-4 and molecular formula C9H15N2O14P3 · xNa+. It is used in various industrial and research applications.

Applications

2′-Deoxyuridine 5′-triphosphate (dUTP) may be used to study the distribution, specificity and kinetics of deoxyuridine 5′-triphosphate nucleotidohydrolase(s) (dUTPase, EC 3.6.1.23). dUTPase are important enzymes that protect cells from the incorporation of dUTP into DNA.dUTP is a component of the TUNEL (terminal deoxyribonucleotidyl-transferase-(TdT)-mediated deoxyuridine-5′-triphosphate- (dUTP) nick-end labeling) test. TUNEL is a common method for detecting DNA fragmentation that results from apoptotic signaling cascades.

Specifications

Molecular Weight

468.14 (free acid basis) g/mol

Assay/Purity

≥95%

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