Z-L-Phe chloromethyl ketone
Z-L-Phe chloromethyl ketone (CAS 26049-94-5) is a chemical compound with the linear formula C6H5CH2CH(NHCO2CH2C6H5)COCH2Cl and a molecular weight of 331.79 g/mol. It is primarily recognised for its application as an enzyme inhibitor. This compound is of interest in various biological and chemical research fields, including cell biology and chemical synthesis.
- IUPAC
- NSC 251810, SL-01,N-Carbobenzyloxy-L-phenylalanyl chloromethyl ketone,ZPCK
- Synonyms
- N-Carbobenzyloxy-L-phenylalanyl chloromethyl ketoneZPCKSL-01NSC 251810

Enzyme Inhibition
Z-L-Phe chloromethyl ketone functions as an enzyme inhibitor, with specific reference to chymotrypsin A gamma from bovine sources. Its mechanism of action is important for biochemical research and understanding enzyme function.
Chemical Synthesis
As a phenylalanine derivative and unnatural amino acid derivative, this compound can serve as a building block or intermediate in complex chemical synthesis pathways. Its structure offers unique reactivity for organic chemistry applications.
Cell Biology Research
The compound's role as an enzyme inhibitor makes it a valuable tool in cell biology and cell signalling research. It aids in studying cellular processes affected by the targeted enzymes.
| Molecular weight | 331.79 |
|---|---|
| Linear formula | C6H5CH2CH(NHCO2CH2C6H5)COCH2Cl |
| Assay | 98% |
| Optical activity | [α]23/D +30°, c = 1 in chloroform |
| Storage temperature | −20°C |
| Application | Enzyme inhibitor.1 |
| Melting point | 107-108 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Z-L-Phe chloromethyl ketone used for?
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Z-L-Phe chloromethyl ketone is primarily used as an enzyme inhibitor, particularly in research related to cell biology, cell signalling, and chemical synthesis.
What is the CAS number and chemical formula for Z-L-Phe chloromethyl ketone?
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The CAS number is 26049-94-5, and the linear chemical formula is C6H5CH2CH(NHCO2CH2C6H5)COCH2Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Z-L-Phe chloromethyl ketone with an assay of 98%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should Z-L-Phe chloromethyl ketone be handled?
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Z-L-Phe chloromethyl ketone is classified as Danger (GHS05). It causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection, must be used. Handle only in a well-ventilated area or under a fume hood.
Is Z-L-Phe chloromethyl ketone available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Z-L-Phe chloromethyl ketone, and can fulfil international orders.
How can I request a quote or sample?
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To request a quote or a sample of Z-L-Phe chloromethyl ketone, please contact our sales team through the website or by phone, providing your details and quantity requirements.
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