Wedelolactone
Wedelolactone (CAS: 524-12-9), a coumestan derivative with the molecular formula C16H10O7, is a pale yellow solid. It is known for its bioactive properties and serves as a valuable research chemical. Primarily utilised in cell biology and cell signalling studies, Wedelolactone acts as an inhibitor for I Kappa B Kinase (IKK). Its applications extend to kinase/phosphatase biology research, particularly within serine/threonine kinase pathways.
- IUPAC
- 1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one,7-Methoxy-5,11,12-trihydroxycoumestan
Cell Biology Research
Wedelolactone is employed in cellular studies to investigate biological processes and pathways. Its known inhibitory activity makes it useful for dissecting signalling cascades within cells.
Kinase Inhibition Studies
As an inhibitor of I Kappa B Kinase (IKK), Wedelolactone is a key reagent for researchers studying kinase/phosphatase biology. It aids in understanding the role of serine/threonine kinases in cellular functions.
Cell Signalling Investigations
This compound is used to probe cell signalling pathways, particularly those involving IKK. Its application helps elucidate the mechanisms of signal transduction in neuroscience and other biological contexts.
| Molecular weight | 314.25 |
|---|---|
| Empirical formula | C16H10O7 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | pale yellow |
| Solubility | DMSO: soluble >10 mg/mL |
| Storage temperature | 2-8°C |
Hazard statements
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-43 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Wedelolactone used for?
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Wedelolactone is primarily used in research for cell biology, cell signalling, and kinase inhibition studies, particularly targeting I Kappa B Kinase (IKK).
What are the CAS number and formula for Wedelolactone?
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The CAS number for Wedelolactone is 524-12-9, and its molecular formula is C16H10O7.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Wedelolactone with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should Wedelolactone be handled and stored?
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Wedelolactone is a Warning substance (GHS07) that is harmful if swallowed and may cause an allergic skin reaction. It should be handled with appropriate personal protective equipment, including a dust mask (N95), eyeshields, faceshields, and gloves. Store at 2-8°C.
Is Wedelolactone a controlled substance?
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The provided data does not indicate that Wedelolactone is a controlled substance.
How are Wedelolactone products packaged and shipped?
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Wedelolactone is supplied as a solid in pale yellow form. TSS exports fine chemicals globally, ensuring appropriate packaging for safe transport.
How can I request a quote or sample of Wedelolactone?
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To request a quote or sample of Wedelolactone, please contact our sales team through the TSS website or via your usual established communication channel.
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