Tropicamide
Tropicamide (CAS: 1508-75-4, Formula: C17H20N2O2, MW: 284.35) is a white solid compound. It functions as an anticholinergic agent, primarily used in ophthalmic applications for mydriasis (pupil dilation) and cycloplegia. It is also utilised in research settings for studying neurological pathways and behaviours, such as its use in investigating fragile X syndrome-related behaviours in male mice and pupil dilation studies.
- IUPAC
- N-Ethyl-2-phenyl-N-(4-pyridylmethyl)hydracrylamide,Ro 1-7683
- Synonyms
- N-Ethyl-2-phenyl-N-(4-pyridylmethyl)hydracrylamideRo 1-7683
Ophthalmic Research
Tropicamide is employed in ophthalmic research for its mydriatic properties, facilitating pupil dilation for examinations. It is also used to induce cycloplegia, which aids in the study of accommodation and refractive error.
Neuroscience Research
This compound has been utilised in preclinical research to study neurological functions. For instance, it has been used to investigate the regulation of behaviours associated with fragile X syndrome in male mouse models.
Pharmacological Studies
Tropicamide serves as a valuable tool in pharmacological studies investigating cholinergic systems. Its specific action on muscarinic acetylcholine receptors makes it useful for understanding neurotransmission.
| Molecular weight | 284.35 |
|---|---|
| Empirical formula | C17H20N2O2 |
| Form | solid |
| Colour | white |
| Solubility | 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble4.3 mg/mLethanol: soluble5.6 mg/mLH2O: insoluble |
| Storage temperature | 2-8°C |
| Application | Tropicamide has been used for studying the regulation of fragile X behavior in male mice1. 1% tropicamide has also been used for dilating mice pupils2. |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38-42/43 |
| Safety statements (S) | 22-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CHRM4(1132) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tropicamide used for?
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Tropicamide is primarily used in ophthalmology for mydriasis (pupil dilation) and cycloplegia. It is also used in research, including studies on neurological behaviours and cholinergic systems.
What is the CAS number and chemical formula for Tropicamide?
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The CAS number for Tropicamide is 1508-75-4, and its chemical formula is C17H20N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tropicamide as a research-grade chemical. The specific purity assay is available on the product's Certificate of Analysis. TSS does not represent this product as USP, BP, or EP grade.
How should Tropicamide be handled safely?
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Tropicamide is classified as a Warning substance. It may be harmful if swallowed, in contact with skin, or if inhaled. It can also cause skin and eye irritation, and may cause respiratory irritation. Always consult the Safety Data Sheet (SDS) for full handling precautions and wear appropriate personal protective equipment (PPE).
Is Tropicamide a controlled substance?
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The provided data does not indicate that Tropicamide is a controlled substance. However, regulations can vary by jurisdiction.
How is Tropicamide packed, shipped, and exported?
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Tropicamide is carefully packed to ensure stability and safety during transit. Tech Serve Solutions is an experienced global exporter of chemicals, adhering to all relevant shipping regulations.
How can I request a quote or sample for Tropicamide?
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To request a quote or sample of Tropicamide, please contact our sales team through the TSS website or via email, providing your specific requirements and shipping details.
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