Trichlorododecylsilane

CAS 4484-72-4CH3(CH2)11SiCl3Chemical Synthesis

Trichlorododecylsilane (CAS: 4484-72-4), with the linear formula CH₃(CH₂)₁₁SiCl₃ and a molecular weight of 303.77 g/mol, is a silicon-based chemical reagent. It is primarily utilised in chemical synthesis as a protecting and derivatizing agent. Its reactive trichlorosilyl group allows for facile functionalization, making it valuable in organic chemistry for modifying molecules and introducing specific properties.

IUPAC: Dodecyltrichlorosilane

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Trichlorododecylsilane (CH3(CH2)11SiCl3) — chemical structure, CAS 4484-72-4; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical SynthesisSilicon-BasedSynthetic Reagents

01 /Applications

Protecting Group Chemistry

Trichlorododecylsilane serves as an effective reagent for the protection of hydroxyl and amine functionalities in organic synthesis. The dodecyl chain provides lipophilicity, aiding in solubility and subsequent separation processes.

Surface Modification

This silane can be employed to modify the surface properties of materials, such as silica or glass. It can create hydrophobic or chemically reactive surfaces, useful in chromatography or material science applications.

Derivatization for Analysis

In analytical chemistry, it can be used to derivatize compounds to improve their volatility or detectability by techniques like gas chromatography (GC).

02 /Properties

Molecular weight	303.77
Linear formula	CH3(CH2)11SiCl3
Assay	≥95.0% (GC)
Boiling point	293-294 °C(lit.)
Density	1.02 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.454(lit.)n20/D 1.454

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Protective equipment	Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point	110 °C / 230 °F
Transport (UN / ADR)	UN 1771 8 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	C
Risk statements (R)	34-37
Safety statements (S)	26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

4484-72-4

MDL number

MFCD00000483

Beilstein registry

1758004

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Trichlorododecylsilane used for?

Trichlorododecylsilane is primarily used in chemical synthesis as a protecting and derivatizing reagent for hydroxyl and amine groups, and for surface modification.

What are the CAS number and chemical formula for Trichlorododecylsilane?

The CAS number is 4484-72-4 and the linear formula is CH₃(CH₂)₁₁SiCl₃.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Trichlorododecylsilane with an assay of ≥95.0% (GC). This product is typically supplied for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.

How should Trichlorododecylsilane be handled safely?

Trichlorododecylsilane is corrosive and can cause severe skin burns and eye damage (H314). Handling requires appropriate personal protective equipment, including gloves, goggles, a facesheild, and a suitable respirator. It reacts with moisture, so work should be conducted in a dry environment.

How is Trichlorododecylsilane packed, shipped, and exported?

Trichlorododecylsilane is packed according to international shipping regulations for hazardous materials, including UN 1771, Class 8, Packing Group II. TSS exports globally, adhering to all relevant transport and customs requirements.

How can I request a sample or quote for Trichlorododecylsilane?

To request a sample or a quote, please visit the Tech Serve Solutions website and use the online enquiry form or contact our sales team directly with your requirements.