Tideglusib

CAS 865854-05-3C19H14N2O2SCell Biology

Tideglusib (CAS: 865854-05-3), with the empirical formula C19H14N2O2S and a molecular weight of 334.39 g/mol, is a potent inhibitor of Glycogen Synthase Kinase 3 (GSK3). This compound is primarily utilised in scientific research, particularly in studies concerning neurodegenerative diseases, cell signalling, and neuroscience. Available as a white to beige powder, Tideglusib plays a role in advancing our understanding of cellular pathways relevant to various biological processes.

IUPAC: 4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione,NP-12,NP031112
Synonyms: 4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dioneNP-12NP031112

Email us

Tideglusib (C19H14N2O2S) — chemical structure, CAS 865854-05-3; Life Science, fine chemical supplied by Tech Serve Solutions

Alzheimer′s DiseaseCell BiologyKinase/Phosphatase BiologyNeurobiologyNeuroscience

01 /Applications

Neuroscience Research

Tideglusib is extensively used as a research tool in neuroscience to investigate the role of GSK3 in neuronal function and disease pathogenesis. Its inhibitory action on GSK3 makes it valuable for studying pathways implicated in conditions like Alzheimer's disease and other neurodegenerative disorders.

Cell Signalling Studies

As a selective GSK3 inhibitor, Tideglusib aids in elucidating the complex cellular signalling cascades regulated by this enzyme. Researchers employ it to understand GSK3's involvement in processes such as cell proliferation, apoptosis, and metabolic regulation.

Alzheimer's Disease Research

This compound is a key reagent in Alzheimer's disease research due to GSK3's known role in the phosphorylation of tau protein, a hallmark of the disease. Tideglusib helps researchers explore potential therapeutic strategies targeting GSK3.

Kinase/Phosphatase Biology

Tideglusib serves as a critical tool for investigating the broader field of kinase and phosphatase biology. Its specificity allows for targeted studies into the functional outcomes of inhibiting serine/threonine kinases like GSK3.

02 /Properties

Molecular weight	334.39
Empirical formula	C19H14N2O2S
Assay	≥98% (HPLC)
Form	powder
Colour	white to beige
Solubility	DMSO: >15 mg/mL
Storage temperature	2-8°C

03 /Identifiers & registry

CAS number

865854-05-3

04 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is Tideglusib used for?

Tideglusib is primarily used in scientific research, particularly for studying Glycogen Synthase Kinase 3 (GSK3), neuroscience, cell signalling, and neurodegenerative diseases such as Alzheimer's.

What is the CAS number and formula for Tideglusib?

The CAS number for Tideglusib is 865854-05-3, and its empirical formula is C19H14N2O2S.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Tideglusib with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should Tideglusib be handled and stored?

Tideglusib is supplied as a white to beige powder. It is classified under WGK Germany 3, indicating a high hazard to water. Store at 2-8°C. Handle with appropriate personal protective equipment in a well-ventilated area.

Is Tideglusib a controlled substance?

The provided data does not indicate that Tideglusib is a scheduled or controlled substance.

How is Tideglusib packed and exported?

Tideglusib is typically supplied as a powder in various pack sizes suitable for laboratory research. As a global supplier, Tech Serve Solutions exports chemicals worldwide, adhering to all relevant shipping regulations.

How can I request a sample or quote for Tideglusib?

To request a sample or a quote for Tideglusib, please contact the Tech Serve Solutions sales team via our website or by phone, referencing the product name and CAS number 865854-05-3.