Tetramethylphosphonium bromide
Tetramethylphosphonium bromide (CAS: 4519-28-2) is a quaternary phosphonium salt with the linear formula (CH3)4P(Br). This compound functions primarily as a phase transfer catalyst and a synthetic reagent in various chemical processes. With a molecular weight of 171.02 g/mol, it is supplied by Tech Serve Solutions with an assay of 98%, suitable for laboratory research and chemical synthesis applications.

Phase Transfer Catalysis
Tetramethylphosphonium bromide acts as an effective phase transfer catalyst, facilitating reactions between reactants located in different immiscible phases. Its quaternary phosphonium structure enables the transfer of anions into organic phases, thereby increasing reaction rates and yields in nucleophilic substitution and alkylation reactions.
Chemical Synthesis
As a synthetic reagent, this phosphonium salt is employed in diverse organic transformations. It can serve as a source of the tetramethylphosphonium cation in various synthetic routes, contributing to the formation of complex organic molecules. Its utility is found in academic research and industrial process development.
Precursor for Phosphonium Compounds
This compound can be utilised as a starting material or intermediate for the synthesis of other functionalised phosphonium salts. These derivatives may possess tailored properties for specific catalytic or material science applications.
| Molecular weight | 171.02 |
|---|---|
| Linear formula | (CH3)4P(Br) |
| Assay | 98% |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tetramethylphosphonium bromide used for?
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Tetramethylphosphonium bromide (CAS: 4519-28-2) is primarily used as a phase transfer catalyst and a synthetic reagent in chemical synthesis. It facilitates reactions between different phases and can be a precursor for other phosphonium compounds.
What are the CAS number and formula for Tetramethylphosphonium bromide?
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The CAS number for Tetramethylphosphonium bromide is 4519-28-2, and its linear formula is (CH3)4P(Br).
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tetramethylphosphonium bromide with an assay of 98%. This product is suitable for research and general chemical synthesis purposes and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should Tetramethylphosphonium bromide be handled safely?
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Tetramethylphosphonium bromide is classified with the GHS signal word 'Warning' and has hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust. In case of contact, rinse thoroughly and seek medical advice if irritation persists.
How is Tetramethylphosphonium bromide packed and exported?
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Tetramethylphosphonium bromide is carefully packed to ensure safe transit and is available for global export by Tech Serve Solutions, adhering to all necessary shipping regulations for chemical substances.
How can I request a quote or sample?
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To request a quote or a sample of Tetramethylphosphonium bromide, please contact our sales team through the website or by direct inquiry, providing your specific requirements.
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