Sunitinib malate
Sunitinib malate (CAS: 341031-54-7), a key pharmaceutical compound with the molecular formula C22H27FN4O2 · C4H6O5 and a molecular weight of 532.56, is supplied by TSS as a powder. It functions as a multi-targeted receptor tyrosine kinase (RTK) inhibitor. This bioactive small molecule is integral to research in cell biology, cell signalling, and kinase/phosphatase pathways, particularly in oncology and neuroscience research.
- IUPAC
- N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioic acid (1:1) salt,SU 011248,SU 11248,SU112248
- Synonyms
- N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioic acid (1:1) saltSU 011248SU 11248SU112248
Kinase Inhibitor Research
Sunitinib malate is a potent inhibitor of various receptor tyrosine kinases including VEGFR and PDGFR. It is widely utilised in pre-clinical research to investigate signalling pathways involved in tumour growth and angiogenesis.
Cell Signalling Studies
This compound serves as a valuable tool for researchers studying cellular communication and growth regulation. Its specific inhibition profile makes it useful for dissecting complex intracellular signalling cascades.
Oncology Drug Discovery
As an approved therapeutic agent in certain indications, sunitinib malate is also employed in drug discovery programmes aiming to develop novel anti-cancer therapies targeting tyrosine kinase pathways.
| Molecular weight | 532.56 |
|---|---|
| Empirical formula | C22H27FN4O2 · C4H6O5 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Solubility | DMSO: >10 mg/mL |
| Storage temperature | room temp |
Hazard statements
- H360May damage fertility or the unborn child
- H372Causes damage to organs through prolonged exposure
Precautionary statements
- P201Obtain special instructions before use
- P308IF exposed or concerned
| Water hazard class (WGK, DE) | 2 |
|---|---|
| Hazard codes (EU) | T |
| Risk statements (R) | 61-2-48/25 |
| Safety statements (S) | 53-22-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Sunitinib malate used for?
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Sunitinib malate is primarily used in research settings for its activity as a multi-targeted receptor tyrosine kinase inhibitor, with applications in oncology, cell signalling, and kinase biology research.
What is the CAS number and formula for Sunitinib malate?
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The CAS number for Sunitinib malate is 341031-54-7, and its molecular formula is C22H27FN4O2 · C4H6O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Sunitinib malate with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should Sunitinib malate be handled?
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Sunitinib malate is classified as Danger (GHS08) and carries hazard statements H360 (May damage fertility or the unborn child) and H372 (Causes damage to organs through prolonged or repeated exposure). Handle with appropriate personal protective equipment in a well-ventilated area. Refer to the Safety Data Sheet (SDS) for full details.
How is Sunitinib malate shipped and exported?
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TSS handles the global export of Sunitinib malate, ensuring appropriate packaging and documentation for international shipment.
How can I request a quote or sample?
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To request a quote or a sample of Sunitinib malate, please contact our sales team via the website or phone, providing your specific requirements.
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