SCH-442416
SCH-442416 (CAS: 316173-57-6), with the molecular formula C20H19N7O2 and a molecular weight of 389.41 g/mol, is a bioactive small molecule. It functions as an A<sub>2A</sub> receptor antagonist. This compound has been utilised in research to investigate its effects on infarct size in mice and its role in modulating adenosine receptors in human chondrocyte cells.
- IUPAC
- 2-(2-Furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine; 5-amino-7-(3-(4-methoxyphenyl)propyl)-2-(2 furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine; 5-Amino-7-[3-(4-methoxy)phenylpropyl]-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine
- Synonyms
- 5-amino-7-(3-(4-methoxyphenyl)propyl)-2-(2-furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine5-Amino-7-[3-(4-methoxy)phenylpropyl]-2-(2-furyl)-pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine2-(2-Furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo [4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
A2A Receptor Antagonism
SCH-442416 acts as a selective antagonist for A<sub>2A</sub> receptors. It has been used in preclinical studies to explore the impact of A<sub>2A</sub> receptor blockade on physiological processes.
Cardiovascular Research
This compound was employed to investigate the effect of A<sub>2A</sub> receptor blockade on infarct size in murine models, contributing to the understanding of cardiac injury mechanisms.
Cell Biology Studies
SCH-442416 has been utilised to study the modulation of adenosine receptors in human immortalized chondrocyte cells, aiding research into cellular signalling pathways.
| Molecular weight | 389.41 |
|---|---|
| Empirical formula | C20H19N7O2 |
| Assay | ≥98% (HPLC) |
| Solubility | DMSO: ≥20 mg/mL |
| Storage temperature | 2-8°C |
| Application | SCH-442416 was used to block A2A receptors to study effect on infarct size in mice2 and to study the modulation of adenosine receptors in human immortalized chondrocyte cells.3 |
| Storage Condition | desiccated |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SCH-442416 used for?
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SCH-442416 is used in research as an A<sub>2A</sub> receptor antagonist to study its effects on infarct size in mice and its modulation of adenosine receptors in human chondrocyte cells.
What is the CAS number and formula for SCH-442416?
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The CAS number for SCH-442416 is 316173-57-6 and its molecular formula is C20H19N7O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies SCH-442416 with a purity of ≥98% (HPLC). TSS does not represent this product as USP, BP, EP or other pharmacopoeia grades.
How should SCH-442416 be handled and stored?
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SCH-442416 should be handled with appropriate personal protective equipment. It is classified under WGK Germany 3. Store refrigerated at 2-8°C and keep desiccated.
Can I request a sample or quote for SCH-442416?
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Yes, please contact our sales team or use the online form to request a sample or quote for SCH-442416.
Does Tech Serve Solutions export SCH-442416?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including SCH-442416.
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