SB 220025 trihydrochloride
SB 220025 trihydrochloride (CAS: 197446-75-6), with the molecular formula C18H19FN6 · 3HCl and a molecular weight of 447.76, is a white solid compound. This chemical serves as a valuable tool in biological research, particularly for studies investigating p38-mediated cell signaling pathways. Its specific application within kinase/phosphatase and serine/threonine kinase research makes it a key reagent for understanding cellular processes.
- IUPAC
- 5-(2-Aminopyrimidin-4-yl)-4-(4-fluorophenyl)-1-(4-piperidinyl)imidazole trihydrochloride
p38 MAPK Signaling Studies
SB 220025 trihydrochloride is utilised in research focused on the p38 Mitogen-Activated Protein Kinase (p38MAPK) signaling pathway. It acts as an inhibitor, allowing researchers to investigate the role of this kinase in various cellular processes.
Kinase/Phosphatase Biology Research
This compound is relevant to the study of kinase and phosphatase activity. Its selective inhibition of certain kinases aids in elucidating complex signaling cascades within cell biology.
Neuroscience and Cell Signaling
As a tool for cell signaling research, SB 220025 trihydrochloride contributes to investigations in neuroscience, helping to understand neuronal function and response mechanisms.
| Molecular weight | 447.76 |
|---|---|
| Empirical formula | C18H19FN6 · 3HCl |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | H2O: soluble22 mg/mL |
| Application | SB 220025 trihydrochloride may be used in p38-mediated cell signaling studies. |
Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-36-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is SB 220025 trihydrochloride used for?
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SB 220025 trihydrochloride is used in research for studying p38-mediated cell signaling, kinase/phosphatase biology, and as a bioactive small molecule in cell biology and neuroscience research.
What are the CAS number and formula for SB 220025 trihydrochloride?
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The CAS number for SB 220025 trihydrochloride is 197446-75-6, and its formula is C18H19FN6 · 3HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies SB 220025 trihydrochloride with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations for SB 220025 trihydrochloride?
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SB 220025 trihydrochloride is classified as Dangerous (GHS06, Danger) with hazards including H301 (Toxic if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a P2 respirator, is recommended. Handle with extreme care in a well-ventilated area.
How is SB 220025 trihydrochloride shipped and exported?
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SB 220025 trihydrochloride is shipped and exported according to international regulations for hazardous materials, identified under UN 2811 (6.1 / PGIII).
How can I request a sample or quote for SB 220025 trihydrochloride?
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To request a sample or a quote for SB 220025 trihydrochloride, please contact our sales department through the TSS website or by calling our main office.
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