(S,S)-o-Tolyl-DIPAMP
(S,S)-o-Tolyl-DIPAMP (CAS: 810667-85-7) is a chiral phosphine ligand with a molecular weight of 426.47. This compound plays a crucial role as a privileged ligand in asymmetric synthesis and catalysis. Its well-defined stereochemistry and electronic properties make it highly effective in promoting enantioselective transformations, contributing to the efficient production of chiral molecules in chemical synthesis. TSS supplies this reagent for advanced research and development.
- IUPAC
- (S,S)-1,2-Bis[(o-tolyl)(phenylphosphino)]ethane,(S,S)-1,2-Ethanediylbis[(2-methylphenyl)phenylphosphine]
- Synonyms
- (S,S)-1,2-Bis[(o-tolyl)(phenylphosphino)]ethane(S,S)-1,2-Ethanediylbis[(2-methylphenyl)phenylphosphine]
Asymmetric Catalysis
(S,S)-o-Tolyl-DIPAMP serves as a key chiral ligand in transition metal-catalysed asymmetric reactions. It enables the enantioselective formation of chiral centres, which is critical for synthesising complex molecules with specific stereochemistry.
Chiral Ligand Synthesis
As a prominent member of the DIPAMP ligand family, it is employed in the development and optimisation of catalytic systems for stereoselective synthesis. Its unique structure facilitates high levels of enantioselectivity in various organic transformations.
Pharmaceutical Intermediate Synthesis
This ligand is utilised in synthetic routes for producing chiral pharmaceutical intermediates. Its application is vital for ensuring the stereochemical purity of active pharmaceutical ingredients (APIs).
| Molecular weight | 426.47 |
|---|---|
| Empirical formula | C28H28P2 |
| Assay | 95% |
| Optical activity | [α]22/D +48, c = 1 in chloroform |
| Melting point | 86-90 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S,S)-o-Tolyl-DIPAMP used for?
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(S,S)-o-Tolyl-DIPAMP is primarily used as a chiral ligand in asymmetric synthesis and catalysis, particularly in the development of enantioselective reactions for producing chiral molecules.
What is the CAS number and formula for (S,S)-o-Tolyl-DIPAMP?
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The CAS number is 810667-85-7, and the empirical formula is C28H28P2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S,S)-o-Tolyl-DIPAMP with an assay of 95%. This is typically considered a research or technical grade, and TSS does not represent it as meeting USP, BP, or EP pharmacopoeial standards.
How should (S,S)-o-Tolyl-DIPAMP be handled?
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Handle (S,S)-o-Tolyl-DIPAMP with appropriate personal protective equipment, including a dust mask (N95 type recommended), eyeshields, and gloves. It may cause skin, eye, and respiratory irritation (H315, H319, H335). Ensure adequate ventilation and avoid dust formation.
Is (S,S)-o-Tolyl-DIPAMP a controlled substance?
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The provided data does not indicate that (S,S)-o-Tolyl-DIPAMP is a controlled substance.
How is (S,S)-o-Tolyl-DIPAMP packed and shipped?
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Tech Serve Solutions packs and exports (S,S)-o-Tolyl-DIPAMP following relevant regulations for chemical transport. Specific packaging details depend on order size and destination.
How can I request a sample or quote for (S,S)-o-Tolyl-DIPAMP?
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To request a sample or quote, please contact the Tech Serve Solutions sales team through our website or by phone, providing your details and the product CAS number 810667-85-7.
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