(S)-(+)-Pantolactone
(S)-(+)-Pantolactone (CAS: 5405-40-3), a chiral organic compound with the molecular formula C6H10O3 and a molecular weight of 130.14 g/mol, is a valuable lactone building block. It is primarily utilised in asymmetric synthesis and various chemical synthesis applications where chirality is essential. This compound serves as a key intermediate in the production of pharmaceuticals and other fine chemicals requiring specific stereochemistry, contributing to the development of enantiomerically pure substances.
- IUPAC
- (S)-(+)-α-Hydroxy-β,β-dimethyl-γ-butyrolactone,(S)-(+)-β,β-Dimethyl-α-hydroxy-γ-butyrolactone,(S)-Dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone,L-Pantolactone
- Synonyms
- (S)-(+)-α-Hydroxy-β,β-dimethyl-γ-butyrolactone(S)-(+)-β,β-Dimethyl-α-hydroxy-γ-butyrolactone(S)-Dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanoneL-Pantolactone

Chiral Building Block in Asymmetric Synthesis
(S)-(+)-Pantolactone is a vital chiral synthon used in asymmetric synthesis to introduce stereogenic centres into target molecules. Its defined stereochemistry makes it ideal for the enantioselective construction of complex organic compounds.
Pharmaceutical Intermediate
This lactone is a critical intermediate in the synthesis of various pharmaceutical agents. Its chiral nature is often essential for the biological activity and efficacy of the final drug product, particularly in stereospecific therapeutic applications.
Organic Synthesis
Beyond pharmaceuticals, (S)-(+)-Pantolactone finds application in general organic synthesis as a versatile starting material or intermediate. It is used in the preparation of diverse chiral organic molecules for research and development purposes.
| Molecular weight | 130.14 |
|---|---|
| Empirical formula | C6H10O3 |
| Assay | 99% |
| Boiling point | 120-122 °C/15 mmHg(lit.) |
| Optical activity | [α]20/D +53°, c = 2.4 in H2O |
| Melting point | 89-93 °C |

Hazard statements
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-(+)-Pantolactone used for?
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Tech Serve Solutions supplies (S)-(+)-Pantolactone primarily for use in asymmetric synthesis and as a chiral building block in the preparation of pharmaceuticals and other fine organic chemicals where specific stereochemistry is required.
What are the CAS number and formula for (S)-(+)-Pantolactone?
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The CAS number for (S)-(+)-Pantolactone is 5405-40-3, and its empirical formula is C6H10O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-(+)-Pantolactone with a minimum assay of 99%. We do not represent this product as USP, BP, or EP grade; it is supplied for research and chemical synthesis purposes.
What are the primary safety concerns for (S)-(+)-Pantolactone?
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(S)-(+)-Pantolactone carries a GHS05 symbol and the signal word 'Danger'. It carries the hazard statement H318, which indicates it causes serious eye damage. Appropriate personal protective equipment, including eye protection, should always be worn when handling this chemical.
How is (S)-(+)-Pantolactone shipped and exported?
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As a specialist global supplier, Tech Serve Solutions can expertly pack, ship, and export (S)-(+)-Pantolactone worldwide, adhering to all necessary international shipping regulations for chemicals.
How can I request a quote or sample of (S)-(+)-Pantolactone?
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To request a quote or a sample of (S)-(+)-Pantolactone, please contact our sales team directly through our website or by phone.
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