(S)-Duloxetine hydrochloride
(S)-Duloxetine hydrochloride (CAS: 136434-34-9, C18H19NOS · HCl) is a research chemical with a molecular weight of 333.88 g/mol. Supplied as a white to beige powder, it is primarily utilised in biological and chemical research contexts, particularly within neuroscience and cell biology studies focusing on neurotransmission and biogenic amine transport. Its specific enantiomeric form and optical activity make it a valuable tool for targeted research applications.
- IUPAC
- (γS)-N-Methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine hydrochloride,(+)-(S)-N-Methyl-γ-(1-naphthyloxy)-2-thiophenepropylamine hydrochloride,(+)-N-Methyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine hydrochloride,LY-248686 hydrochloride
- Synonyms
- (γS)-N-Methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine hydrochloride(+)-(S)-N-Methyl-γ-(1-naphthyloxy)-2-thiophenepropylamine hydrochloride(+)-N-Methyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine hydrochlorideLY-248686 hydrochloride

Neuroscience Research
Investigates neurotransmitter systems, particularly serotonin and norepinephrine reuptake mechanisms. Useful for studying conditions related to mood disorders and neurological function.
Biogenic Amine Transport Studies
Serves as a tool to probe the function and inhibition of biogenic amine transporters in cellular and biochemical assays.
Cell Biology Investigations
Employed in cell signaling research to understand the molecular pathways influenced by neurotransmitter modulation.
Pharmacological Tool
A valuable reagent for in vitro and in vivo research models exploring drug mechanisms of action related to its targeted biochemical pathways.
| Molecular weight | 333.88 |
|---|---|
| Empirical formula | C18H19NOS · HCl |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | H2O: soluble5 mg/mL (clear solution, warmed) |
| Optical activity | [α]/D +116 to +125°, c = 1 in methanol |
| Storage temperature | room temp |

Hazard statements
- H302Harmful if swallowed
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-Duloxetine hydrochloride primarily used for?
+
It is used in scientific research, particularly in neuroscience, cell biology, and studies concerning biogenic amine transport and neurotransmission.
What is the CAS number and chemical formula for (S)-Duloxetine hydrochloride?
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The CAS number is 136434-34-9 and the empirical formula is C18H19NOS · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-Duloxetine hydrochloride with an assay of ≥98% (HPLC). TSS does not represent this product as USP, BP, EP, or any pharmacopoeia grade.
What are the safety considerations when handling (S)-Duloxetine hydrochloride?
+
This compound is classified under GHS07 with a Warning signal word, indicating hazards such as H302 (Harmful if swallowed). Handle with appropriate personal protective equipment in a well-ventilated area. Consult the Safety Data Sheet (SDS) for detailed handling and safety information.
Is (S)-Duloxetine hydrochloride a controlled substance?
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The provided data does not indicate that (S)-Duloxetine hydrochloride is a controlled substance. However, users should always verify local regulations.
How is (S)-Duloxetine hydrochloride shipped and exported?
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(S)-Duloxetine hydrochloride is typically shipped and exported as a powder under ambient conditions, adhering to all necessary international shipping regulations for research chemicals.
How can I request a sample or quote for (S)-Duloxetine hydrochloride?
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To request a sample or a quotation, please visit the Tech Serve Solutions website or contact our sales department directly with your inquiry.
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