(S)-3-Amino-1,2-propanediol
(S)-3-Amino-1,2-propanediol (CAS 61278-21-5) is a chiral amino alcohol with a molecular weight of 91.11 g/mol. This compound serves as a valuable building block in asymmetric synthesis and organic chemistry. Its unique structure, featuring both an amine and two hydroxyl groups, makes it suitable for diverse applications in chemical synthesis, particularly in the creation of complex chiral molecules.
- Synonyms
- H2NCH2CH(OH)CH2OH
Chiral Building Block
(S)-3-Amino-1,2-propanediol is extensively utilized as a chiral synthon in the construction of enantiomerically pure compounds. Its defined stereochemistry allows for precise control in multi-step synthetic pathways, crucial for pharmaceutical and fine chemical development.
Asymmetric Synthesis
This amino alcohol is employed in various asymmetric transformations and methodologies. It facilitates the development of stereoselective reactions, contributing to the efficient synthesis of optically active target molecules.
Organic Synthesis Intermediate
As a versatile intermediate, it finds application in the synthesis of a wide range of organic molecules. The presence of amine and diol functionalities offers multiple points for chemical modification and derivatization.
| Molecular weight | 91.11 |
|---|---|
| Linear formula | H2NCH2CH(OH)CH2OH |
| Assay | 98% |
| Boiling point | 117-119 °C/0.4 mmHg(lit.) |
| Density | 1.175 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.483(lit.) |
| Optical activity | [α]23/D −12±2° (neat or melt) |
| Impurities tested | <0.5 mol |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3259PSN1 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-3-Amino-1,2-propanediol used for?
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(S)-3-Amino-1,2-propanediol is primarily used as a chiral building block and intermediate in asymmetric synthesis and general organic chemistry for the creation of complex chiral molecules.
What is the CAS number and formula for (S)-3-Amino-1,2-propanediol?
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The CAS number for (S)-3-Amino-1,2-propanediol is 61278-21-5. Its linear formula is H₂NCH₂CH(OH)CH₂OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-3-Amino-1,2-propanediol with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should (S)-3-Amino-1,2-propanediol be handled?
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This compound is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection, must be used. Handle in accordance with safety data sheet instructions.
How is (S)-3-Amino-1,2-propanediol shipped?
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(S)-3-Amino-1,2-propanediol is shipped internationally as UN 3259, Class 8, Packing Group II. TSS ensures compliance with all relevant shipping regulations for hazardous materials.
How can I request a sample or quote?
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To request a sample or a quote for (S)-3-Amino-1,2-propanediol, please contact our sales department through the TSS website or via direct inquiry.
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