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(R)-(−)-2-Fluoro-α-methyl-4-biphenylacetic acid

CAS 51543-40-9C6H5C6H3(F)CH(CH3)CO2HChemical Synthesis

(R)-(−)-2-Fluoro-α-methyl-4-biphenylacetic acid (CAS 51543-40-9), with the molecular formula C6H5C6H3(F)CH(CH3)CO2H and a molecular weight of 244.26, is a fluorinated carboxylic acid. It serves as a valuable chiral building block in organic synthesis. This compound is primarily utilised in research and development settings for the synthesis of complex molecules and in asymmetric synthesis applications.

IUPAC
(R)-2-Flurbiprofen,Tarenflurbil
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(R)-(−)-2-Fluoro-α-methyl-4-biphenylacetic acid (C6H5C6H3(F)CH(CH3)CO2H) — chemical structure, CAS 51543-40-9; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisBioactive Small MoleculesBuilding BlocksC13-C26Carboxylic AcidsCell BiologyChemical SynthesisChiral Building BlocksFluorinated Building BlocksOrganic Building Blocks
01 /Applications

Chiral Building Block

This compound is a chiral molecule, making it a useful synthon for constructing stereochemically defined molecules in pharmaceutical and fine chemical research.

Organic Synthesis Intermediate

Its structure, featuring a fluorinated biphenyl moiety and a carboxylic acid group, allows for diverse chemical transformations in multi-step synthetic routes.

Research and Development

Primarily used in laboratory settings for the exploration of new chemical entities and synthetic methodologies, particularly within medicinal chemistry and materials science.

02 /Properties
Molecular weight244.26
Linear formulaC6H5C6H3(F)CH(CH3)CO2H
Assay97%
Melting point110-113 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Toxic (GHS06)
Toxic
Danger

Hazard statements

  • H301Toxic if swallowed

Precautionary statements

  • P301IF SWALLOWED
Protective equipmentEyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Transport (UN / ADR)UN 2811 6.1 / PGIII
Water hazard class (WGK, DE)3
Hazard codes (EU)T
Risk statements (R)25
Safety statements (S)26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
51543-40-9
MDL number
MFCD00869714
05 /Additional specifications
Gene Informationhuman ... IL8RA(3577)
06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is (R)-(−)-2-Fluoro-α-methyl-4-biphenylacetic acid used for?

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(R)-(−)-2-Fluoro-α-methyl-4-biphenylacetic acid is primarily used as a chiral building block in organic synthesis and in research and development for creating complex molecules.

What are the CAS number and formula for this compound?

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The CAS number is 51543-40-9 and the molecular formula is C6H5C6H3(F)CH(CH3)CO2H.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this chemical with an assay of 97%. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade.

How should this chemical be handled safely?

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This compound is classified as acutely toxic if swallowed (H301) and requires careful handling. Use with appropriate personal protective equipment, including eyeshields, face shields, gloves, and P2 respirator cartridges (EN 143). In case of accidental ingestion, seek immediate medical attention (P301 + P310).

Is this product available for export?

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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals and can ship this product internationally.

How can I request a sample or quote for (R)-(−)-2-Fluoro-α-methyl-4-biphenylacetic acid?

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Please contact our sales department directly through our website or by phone to request a sample or a formal quotation.

Need (R)-(−)-2-Fluoro-α-methyl-4-biphenylacetic acid in a specific grade or volume?