Polyethylene glycol monomethyl ether mesylate
Polyethylene glycol monomethyl ether mesylate (CAS: 175172-61-9) is a versatile chemical intermediate with the linear formula CH3O(CH2CH2O)nSO2CH3. This monofunctional polyethylene glycol derivative features a mesylate leaving group, making it valuable in organic synthesis. It is commonly employed in materials science and polymer chemistry for modifications and functionalizations requiring controlled chain extension or surface attachment.
- IUPAC
- O-Mesyl-O′-methyl-polyethylene glycol,mono-Methyl polyethylene glycol mesylate

Polymer Functionalization
Utilised as a building block for creating functionalized polymers. The mesylate group serves as an excellent leaving group for nucleophilic substitution reactions, enabling the attachment of various moieties to the polyethylene glycol chain.
Materials Science
Applied in the development of advanced materials. Its structure allows for tuning the properties of surfaces, nanoparticles, and hydrogels, influencing characteristics such as solubility and biocompatibility.
Organic Synthesis Intermediate
Serves as a key intermediate in multi-step organic synthesis pathways. Its defined structure and reactive mesylate functionality facilitate targeted chemical transformations.
| Linear formula | CH3O(CH2CH2O)nSO2CH3 |
|---|---|
| Melting point | 52-55 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Polyethylene glycol monomethyl ether mesylate used for?
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Polyethylene glycol monomethyl ether mesylate is used in polymer functionalization, materials science, and as an intermediate in organic synthesis. Its primary utility stems from its role as a building block for creating functionalized polymers and modifying materials due to the reactive mesylate group.
What are the CAS number and formula for Polyethylene glycol monomethyl ether mesylate?
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The CAS number for Polyethylene glycol monomethyl ether mesylate is 175172-61-9, and its linear formula is CH3O(CH2CH2O)nSO2CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Polyethylene glycol monomethyl ether mesylate typically as a research or technical grade chemical. The specific assay and purity details are available on the product's specification sheet. We do not represent this product as USP, BP, or EP grade.
How should Polyethylene glycol monomethyl ether mesylate be handled?
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Polyethylene glycol monomethyl ether mesylate is classified as an irritant. Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust. Refer to the Safety Data Sheet (SDS) for comprehensive handling guidelines.
Is Polyethylene glycol monomethyl ether mesylate a controlled substance?
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Based on the provided data, Polyethylene glycol monomethyl ether mesylate (CAS: 175172-61-9) is not indicated as a controlled substance.
How is this chemical shipped and exported?
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Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals. Packaging and shipping adhere to international regulations for hazardous materials, ensuring safe and compliant delivery worldwide.
How can I request a quote or sample?
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To request a quote or a sample of Polyethylene glycol monomethyl ether mesylate, please visit the Tech Serve Solutions website or contact our sales department directly. Our team will be pleased to assist you with your inquiry.
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