Pimonidazole
Pimonidazole (CAS: 70132-50-2), with the empirical formula C11H18N4O3 and a molecular weight of 254.29 g/mol, is a yellow powder. This compound is primarily utilised in research settings for its role in studying cellular processes related to hypoxia and oxidative stress. It serves as a valuable tool in cell biology and biochemical research, aiding in the investigation of cellular responses to stress conditions.
- IUPAC
- NSC 380540,PD 126675;,Ro 03-8799;,alpha-((2-Nitroimidazol-1-yl)methyl)-1-piperidineethanol;,alpha-[(2-Nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol
- Synonyms
- NSC 380540PD 126675Ro 03-8799alpha-((2-Nitroimidazol-1-yl)methyl)-1-piperidineethanolalpha-[(2-Nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol
Hypoxia Detection
Pimonidazole is used as a marker to detect hypoxic regions in cells and tissues. Its reduction under hypoxic conditions allows for the identification of oxygen-deprived areas in biological samples.
Oxidative Stress Research
The compound aids in the study of oxidative stress by interacting with cellular components under conditions of increased reactive oxygen species. This facilitates research into the mechanisms of cellular damage and defence.
Cell Biology Studies
As a bioactive small molecule, Pimonidazole is employed in various cell biology experiments to probe cellular signaling pathways and responses to environmental stresses.
| Molecular weight | 254.29 |
|---|---|
| Empirical formula | C11H18N4O3 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | yellow |
| Solubility | DMSO: >20 mg/mL |
| Storage temperature | 2-8°C |
Hazard statements
- H302Harmful if swallowed
| Hazard codes (EU) | Xn |
|---|---|
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pimonidazole used for?
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Pimonidazole (CAS: 70132-50-2) is used in research for detecting hypoxic regions in cells and tissues and for studying oxidative stress mechanisms.
What is the CAS number and chemical formula for Pimonidazole?
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The CAS number for Pimonidazole is 70132-50-2, and its chemical formula is C11H18N4O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Pimonidazole with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for Pimonidazole?
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Pimonidazole is classified with GHS07 symbol and a 'Warning' signal word, with hazard statement H302 indicating it is harmful if swallowed. Handle with appropriate personal protective equipment in a well-ventilated area.
How is Pimonidazole shipped and exported?
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Pimonidazole is typically stored at 2-8°C. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals.
How can I request a sample or quote for Pimonidazole?
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To request a sample or quote for Pimonidazole, please contact our sales team through the website or by phone.
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