Pentafluoropropionic anhydride
Pentafluoropropionic anhydride (CAS 356-42-3), with the molecular formula (CF<sub>3</sub>CF<sub>2</sub>CO)<sub>2</sub>O and a molecular weight of 310.05 g/mol, is a reactive carboxylic acid anhydride. It is primarily employed as a derivatization reagent in gas chromatography-mass spectrometry (GC-MS) analyses. This includes the determination of stereoisomer content in synthetic peptides and the detection of synephrine in dietary supplements.
- IUPAC
- PFPA,Perfluoropropionic anhydride
- Synonyms
- PFPAPerfluoropropionic anhydride
GC-MS Derivatization Reagent
Pentafluoropropionic anhydride serves as an effective derivatization reagent for GC-MS analysis. It enhances the volatility and detectability of analytes, facilitating precise quantification.
Stereoisomer Analysis
Its application in determining the stereoisomer content of synthetic peptides via GC-MS analysis highlights its utility in stereochemistry and pharmaceutical development.
Synephrine Detection
Used in a GC-MS method for the detection of synephrine in dietary supplements, demonstrating its role in food and supplement quality control and analysis.
| Molecular weight | 310.05 |
|---|---|
| Linear formula | (CF3CF2CO)2O |
| Assay | ≥97.0% (GC) |
| Grade | for GC derivatization |
| Boiling point | 69-70 °C/735 mmHg(lit.) |
| Density | 1.571 g/mL at 25 °C(lit.) |
| Application | Derivatization reagent used in a GC-MS analysis of stereoisomer content of synthetic peptides.1 Also used in a GC-MS detection method for synephrine in dietary supplements.2 |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 14-34 |
| Safety statements (S) | 26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Pentafluoropropionic anhydride used for?
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Pentafluoropropionic anhydride is used as a derivatization reagent in gas chromatography-mass spectrometry (GC-MS) for analysing stereoisomer content in synthetic peptides and for the detection of synephrine in dietary supplements.
What are the CAS number and molecular formula for Pentafluoropropionic anhydride?
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The CAS number for Pentafluoropropionic anhydride is 356-42-3, and its linear formula is (CF<sub>3</sub>CF<sub>2</sub>CO)<sub>2</sub>O.
What grade and purity does Tech Serve Solutions supply for Pentafluoropropionic anhydride?
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Tech Serve Solutions supplies Pentafluoropropionic anhydride with an assay of ≥97.0% (GC), suitable for GC derivatization. We do not represent this product as USP, BP, or EP grade.
How should Pentafluoropropionic anhydride be handled safely?
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Pentafluoropropionic anhydride is corrosive and reacts violently with water. Handle with extreme care, wearing appropriate personal protective equipment including face shields, gloves, goggles, and suitable respirator filters. Ensure adequate ventilation.
How is Pentafluoropropionic anhydride packed, shipped, and exported?
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Pentafluoropropionic anhydride is packed and shipped according to UN 3265, Class 8, Packing Group II regulations. Tech Serve Solutions is a specialist global supplier and exporter.
How can I request a sample or quote for Pentafluoropropionic anhydride?
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To request a sample or quote for Pentafluoropropionic anhydride, please contact our sales department through the TSS website or your dedicated account manager.
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