p-Tolyl chloroformate
p-Tolyl chloroformate (CAS: 937-62-2), with the molecular formula ClCO2C6H4CH3 and a molecular weight of 170.59 g/mol, is an organic acid halide. It serves as a valuable reagent in organic synthesis, primarily functioning as a building block for introducing the p-tolyloxycarbonyl group. Its applications are found in the synthesis of diverse organic compounds and intermediates within chemical research and development.
Organic Synthesis Reagent
p-Tolyl chloroformate is a key intermediate in organic synthesis, enabling the introduction of the p-tolyloxycarbonyl moiety into various molecules. It is utilised in the preparation of esters, carbonates, and carbamates.
Pharmaceutical Intermediate
This compound finds application in the multi-step synthesis of active pharmaceutical ingredients (APIs) and related molecules. Its reactivity makes it suitable for constructing complex organic structures.
Research and Development
As a versatile building block, p-Tolyl chloroformate is employed in academic and industrial research laboratories for developing novel chemical entities and exploring new synthetic pathways.
| Molecular weight | 170.59 |
|---|---|
| Linear formula | ClCO2C6H4CH3 |
| Assay | 97% |
| Boiling point | 99.5 °C/20 mmHg(lit.) |
| Density | 1.188 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5099(lit.) |
| Storage temperature | 2-8°C |
Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H314Causes severe skin burns and eye damage
- H331Toxic if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 86 °C / 186.8 °F |
| Transport (UN / ADR) | UN 3277 6.1/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25-34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is p-Tolyl chloroformate used for?
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p-Tolyl chloroformate is primarily used as a reagent in organic synthesis for introducing the p-tolyloxycarbonyl group into other molecules, finding applications in the preparation of pharmaceuticals and other complex organic compounds.
What are the CAS number and chemical formula for p-Tolyl chloroformate?
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The CAS number for p-Tolyl chloroformate is 937-62-2, and its linear formula is ClCO2C6H4CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies p-Tolyl chloroformate with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should p-Tolyl chloroformate be handled safely?
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p-Tolyl chloroformate is a dangerous substance. Handle with extreme caution, using appropriate personal protective equipment including a face shield, chemical-resistant gloves, and goggles. Ensure adequate ventilation and use a suitable respirator. It is corrosive and toxic by inhalation, skin contact, and ingestion (H301-H311-H314-H331).
How is p-Tolyl chloroformate packed, shipped, and exported?
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p-Tolyl chloroformate is packed according to relevant dangerous goods regulations for safe transport. Tech Serve Solutions is a global supplier and exporter of this chemical.
How can I request a quote or sample for p-Tolyl chloroformate?
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To request a quote or sample for p-Tolyl chloroformate, please contact our sales team through the website or by phone.
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