p-Toluenesulfonyl cyanide
p-Toluenesulfonyl cyanide (CAS: 19158-51-1), with the chemical formula CH3C6H4SO2CN and a molecular weight of 181.21 g/mol, is a specialised organic compound. It serves as a valuable reagent in chemical synthesis, particularly for the preparation of polyfunctional nitriles and in free-radical cyanation reactions. Its utility extends to organic building blocks and nitrogen compound chemistry.
- IUPAC
- p-Tolylsulfonyl cyanide,Tosyl cyanide
Preparation of Polyfunctional Nitriles
p-Toluenesulfonyl cyanide is employed as a key reagent in synthetic pathways leading to the formation of polyfunctional nitriles, contributing to the development of complex organic molecules.
Free-Radical Cyanation
This compound facilitates free-radical cyanation reactions, specifically demonstrated in the cyanation of B-alkylcatecholboranes, enabling specific functional group introduction.
Organic Synthesis Building Block
As an organic building block, p-Toluenesulfonyl cyanide offers versatile reactivity for constructing various carbon skeletons and introducing nitrile functionalities in organic synthesis.
| Molecular weight | 181.21 |
|---|---|
| Linear formula | CH3C6H4SO2CN |
| Assay | 95% |
| Grade | technical grade |
| Boiling point | 105-106 °C/1 mmHg(lit.) |
| Storage temperature | 2-8°C |
| Application | p-Toluenesulfonyl cyanide has been used in:• the preparation of polyfunctional nitriles1• free-radical cyanation of B-alkylcatecholboranes2 |
| Melting point | 47-50 °C(lit.) |
Hazard statements
- H312Harmful in contact with skin
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 20/21-34 |
| Safety statements (S) | 26-27-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is p-Toluenesulfonyl cyanide used for?
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p-Toluenesulfonyl cyanide is used in chemical synthesis, including the preparation of polyfunctional nitriles and free-radical cyanation of B-alkylcatecholboranes.
What is the CAS number and formula for p-Toluenesulfonyl cyanide?
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The CAS number is 19158-51-1, and the chemical formula is CH3C6H4SO2CN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies p-Toluenesulfonyl cyanide in technical grade with an assay of 95%. We do not represent it as USP, BP, or EP grade.
What are the safety and handling considerations for p-Toluenesulfonyl cyanide?
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p-Toluenesulfonyl cyanide is classified as corrosive and toxic upon inhalation and skin contact (H312 + H332, H314). Handling requires stringent safety measures, including appropriate personal protective equipment such as gloves, eyeshields, and respiratory protection, and should be conducted in a well-ventilated area.
How is p-Toluenesulfonyl cyanide packaged and shipped?
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p-Toluenesulfonyl cyanide is exported by Tech Serve Solutions according to international shipping regulations for hazardous materials. Specific packaging details are available upon request.
How can I request a quote or sample for p-Toluenesulfonyl cyanide?
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To request a quote or a sample of p-Toluenesulfonyl cyanide, please contact our sales department through the TSS website or via direct inquiry.
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