N2-Ethyl-2′-deoxyguanosine
N2-Ethyl-2′-deoxyguanosine (CAS: 101803-03-6) is a modified nucleoside with the molecular formula C12H17N5O4 and a molecular weight of 295.29 g/mol. This compound plays a role in biological processes, particularly in cell biology and gene regulation. It is utilised in research settings for studies involving DNA and RNA transcription, cell signalling, and neuroscience, contributing to a deeper understanding of genetic mechanisms and cellular communication pathways.
- IUPAC
- N2-Et-dG

Research in Molecular Biology
N2-Ethyl-2′-deoxyguanosine is employed as a research chemical to investigate DNA structure and function. Its modified nature allows scientists to study the impact of ethylation on DNA-protein interactions and nucleic acid stability.
Cellular Signalling Studies
This compound can be used in research to explore pathways involved in cell signalling. Understanding how modified nucleosides affect cellular responses is crucial for advancing knowledge in cell biology and related fields.
Gene Expression Analysis
Researchers utilise N2-Ethyl-2′-deoxyguanosine in studies focused on gene regulation and expression. It aids in understanding the mechanisms by which genetic information is transcribed and controlled within cells.
Neuroscience Research Applications
The compound finds application in neuroscience research, where modified nucleosides may influence neuronal function or be involved in cellular processes relevant to the nervous system.
| Molecular weight | 295.29 |
|---|---|
| Empirical formula | C12H17N5O4 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white to off-white |
| Solubility | H2O: >5 mg/mL |
| Storage temperature | 2-8°C |


Hazard statements
- H300Fatal if swallowed
- H310Fatal in contact with skin
- H330Fatal if inhaled
- H351Suspected of causing cancer
- H373May cause damage to organs through prolonged exposure
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P301IF SWALLOWED
- P302IF ON SKIN
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 26/27/28-33-40 |
| Safety statements (S) | 36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N2-Ethyl-2′-deoxyguanosine used for?
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N2-Ethyl-2′-deoxyguanosine is primarily used in research for studies in cell biology, cell signalling, neuroscience, and gene regulation and expression. It serves as a tool to investigate DNA transcription and modification effects.
What is the CAS number and formula for N2-Ethyl-2′-deoxyguanosine?
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The CAS number for N2-Ethyl-2′-deoxyguanosine is 101803-03-6, and its molecular formula is C12H17N5O4.
What grade and purity does Tech Serve Solutions supply for N2-Ethyl-2′-deoxyguanosine?
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Tech Serve Solutions supplies N2-Ethyl-2′-deoxyguanosine with a purity of ≥98% (HPLC). This product is intended for research purposes and is not represented as USP, BP, EP, or any pharmacopoeial grade.
How should N2-Ethyl-2′-deoxyguanosine be handled safely?
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N2-Ethyl-2′-deoxyguanosine is classified with a Danger signal word and carries severe hazard statements including H300 (Fatal if swallowed), H310 (Fatal in contact with skin), and H330 (Fatal if inhaled). Handling requires extreme caution, including the use of eyeshields, faceshields, gloves, and P2 respirator cartridges. Always consult the Safety Data Sheet (SDS) and follow appropriate laboratory safety protocols.
Is N2-Ethyl-2′-deoxyguanosine a controlled substance?
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The provided data does not indicate that N2-Ethyl-2′-deoxyguanosine is a controlled substance.
How is N2-Ethyl-2′-deoxyguanosine packed and shipped?
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N2-Ethyl-2′-deoxyguanosine is supplied as a white to off-white solid. It is stored at 2-8°C. As a specialist global supplier, Tech Serve Solutions ensures appropriate packaging and adherence to shipping regulations for international export.
How can I request a sample or quote for N2-Ethyl-2′-deoxyguanosine?
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To request a sample or quote for N2-Ethyl-2′-deoxyguanosine, please visit the Tech Serve Solutions website or contact our sales department directly with your inquiry, referencing the product name and CAS number.
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