N-Boc-piperidine-4-boronic acid pinacol ester
N-Boc-piperidine-4-boronic acid pinacol ester (CAS: 1048970-17-7, C16H30BNO4) is a protected boronic acid derivative. This organometallic reagent is primarily utilised in organic synthesis, particularly in cross-coupling reactions. Its structure incorporates a Boc-protected piperidine ring and a boronate ester moiety, making it a valuable building block for introducing piperidine scaffolds into complex molecules. Supplied by Tech Serve Solutions with an assay of 97%.
- IUPAC
- tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-piperidine-1-carboxylate
Suzuki-Miyaura Cross-Coupling Reactions
N-Boc-piperidine-4-boronic acid pinacol ester serves as a key coupling partner in palladium-catalysed Suzuki-Miyaura reactions. It facilitates the formation of carbon-carbon bonds, enabling the synthesis of diverse biaryl compounds and other complex organic structures.
Medicinal Chemistry and Drug Discovery
This compound is frequently employed in medicinal chemistry programmes for the synthesis of novel drug candidates. The piperidine moiety is a common structural motif in pharmaceuticals, and this reagent allows for its efficient incorporation into lead compounds.
Organic Synthesis Building Block
As a versatile building block, it is integral to multi-step synthetic pathways. The protected nature of the amine and the reactivity of the boronate ester allow for selective functionalization and elaboration of molecules.
| Molecular weight | 311.22 |
|---|---|
| Empirical formula | C16H30BNO4 |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Melting point | 60-65 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-piperidine-4-boronic acid pinacol ester primarily used for?
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N-Boc-piperidine-4-boronic acid pinacol ester is primarily used as a building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions, and in medicinal chemistry for drug discovery.
What is the CAS number and chemical formula for N-Boc-piperidine-4-boronic acid pinacol ester?
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The CAS number is 1048970-17-7, and the chemical formula is C16H30BNO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Boc-piperidine-4-boronic acid pinacol ester with an assay of 97%. This is a research or technical grade chemical and is not represented as USP, BP, EP, or other pharmacopoeial standards.
What are the safety and handling precautions for this compound?
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This compound is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, ensure good ventilation, and avoid contact with skin, eyes, and clothing. Store at 2-8°C.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions carefully packs and ships chemicals in compliance with all relevant national and international regulations. We have extensive experience exporting fine chemicals globally.
How can I request a sample or a quote for N-Boc-piperidine-4-boronic acid pinacol ester?
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To request a sample or a quote, please contact our sales team through the website or by phone, referencing the product name and CAS number.
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