N-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyltolylsulfonamide
N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)tolylsulfonamide (CAS 674776-54-6) is an organoboron compound with the molecular formula C19H24BNO4S. This aryl boronate ester serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions. Its structure, featuring both a boronate ester and a sulfonamide moiety, allows for diverse chemical transformations, making it a key intermediate for researchers in pharmaceutical and materials science.
- IUPAC
- 4-(p-Toluenesulfonylamino)phenylboronic acid pinacol ester,N-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-p-toluenesulfonamide
- Synonyms
- 4-(p-Toluenesulfonylamino)phenylboronic acid pinacol esterN-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-p-toluenesulfonamide

Organic Synthesis Intermediate
Utilised as a building block in the synthesis of complex organic molecules, particularly via Suzuki-Miyaura cross-coupling reactions. It enables the formation of carbon-carbon bonds, crucial for constructing pharmaceutical candidates and advanced materials.
Cross-Coupling Reactions
Acts as a key reagent in palladium-catalyzed cross-coupling reactions, allowing for the introduction of substituted aryl or heteroaryl groups. This is fundamental in medicinal chemistry for drug discovery and development.
Materials Science Research
Its unique structural features make it suitable for incorporation into novel polymers, organic electronic materials, and other advanced materials requiring specific functional properties.
| Molecular weight | 373.27 |
|---|---|
| Empirical formula | C19H24BNO4S |
| Assay | 97% |
Hazard statements
- H413May cause long-lasting harmful effects to aquatic life
| Water hazard class (WGK, DE) | 3 |
|---|
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)tolylsulfonamide used for?
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This compound is primarily used as a building block in organic synthesis, particularly in cross-coupling reactions like the Suzuki-Miyaura coupling, and in materials science research.
What is the CAS number and molecular formula for this product?
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The CAS number is 674776-54-6, and the molecular formula is C19H24BNO4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 97%. It is supplied as a research or technical grade material and is not represented as USP, BP, EP, or any other pharmacopoeial standard.
What are the safety and handling considerations for this chemical?
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This compound carries the hazard statement H413, indicating it may cause long lasting harmful effects to aquatic life. Appropriate personal protective equipment should be worn, and it should be handled in a well-ventilated area, avoiding release into the environment.
How are these chemicals packed and shipped?
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Tech Serve Solutions specialises in the global supply and export of fine chemicals, pharmaceutical intermediates, and laboratory reagents, ensuring appropriate packaging and shipping protocols are followed.
How can I request a sample or a quote?
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To request a sample or obtain a quotation, please contact our sales team via the details provided on our website.
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