Methylzinc chloride solution
Methylzinc chloride solution (CAS 5158-46-3), with the linear formula CH₃ZnCl and a molecular weight of 115.88 g/mol, is a reactive organometallic reagent. Supplied as a solution in Tetrahydrofuran (THF) at a concentration of 2.0 M, it is primarily utilised in organic synthesis. Its applications span various chemical transformations, acting as a key intermediate in the formation of carbon-carbon bonds and other functional group interconversions in complex molecule synthesis.
Organometallic Synthesis
As an organozinc halide, Methylzinc chloride solution serves as a versatile reagent in organometallic chemistry. It is employed in cross-coupling reactions and other C-C bond-forming processes.
Organic Synthesis Intermediate
This compound is frequently used as an intermediate in the synthesis of complex organic molecules. Its controlled reactivity allows for selective functionalization in multi-step synthetic pathways.
Reagent for Alkylation
Methylzinc chloride acts as an effective methylating agent in various organic transformations. It can be used to introduce methyl groups onto diverse substrates under specific reaction conditions.
| Molecular weight | 115.88 |
|---|---|
| Linear formula | CH3ZnCl |
| Boiling point | 67 °C |
| Density | 1.033 g/mL at 25 °C |
| Concentration | 2.0 M in THF |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -17 °C / 1.4 °F |
| Transport (UN / ADR) | UN 1993BF 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-19-34-37-40 |
| Safety statements (S) | 16-26-36/37/39-45 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methylzinc chloride solution used for?
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Methylzinc chloride solution is primarily used in organic synthesis as an organometallic reagent for carbon-carbon bond formation and as a methylating agent.
What is the CAS number and formula for Methylzinc chloride solution?
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The CAS number for Methylzinc chloride solution is 5158-46-3, and its linear formula is CH₃ZnCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methylzinc chloride solution typically as a 2.0 M solution in THF. TSS does not represent this product as USP, BP, EP or other pharmacopoeia grades unless explicitly stated.
How should Methylzinc chloride solution be handled safely?
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Methylzinc chloride solution is highly flammable and corrosive, and may form explosive peroxides. Handle with extreme care in a well-ventilated area, wearing appropriate personal protective equipment including gloves, eye protection, and respiratory protection. Refer to the Safety Data Sheet for detailed handling instructions.
How is Methylzinc chloride solution packed, shipped, and exported?
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Methylzinc chloride solution is classified under UN 1993 BF 3 / PG II and is carefully packaged for safe transport. Tech Serve Solutions offers global export services for this product.
How can I request a sample or quote for Methylzinc chloride solution?
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To request a sample or a quote for Methylzinc chloride solution, please contact the Tech Serve Solutions sales team via our website or designated contact channels.
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