Methyl vinyl sulfone
Methyl vinyl sulfone (CAS: 3680-02-2) is a versatile organic compound with the molecular formula C3H6O2S and a molecular weight of 106.14 g/mol. This sulfone derivative serves as a valuable building block in chemical synthesis and finds applications in the modification of materials and analytical chemistry. Available from Tech Serve Solutions, it is supplied with an assay of 98%.

Analytical Derivatization
Methyl vinyl sulfone can be employed as a derivatization reagent, notably in advanced capillary HPLC-mass spectrometry methods for the sensitive detection of pseudouridine within nucleoside mixtures.
Material Modification
It is utilised in the preparation of methylsulfonylethyl cellulose through a Michael addition reaction with cotton fabric, offering potential for modified cellulosic materials.
Organic Synthesis
The compound participates in organic reactions, including Heck vinylation of aryl halides, demonstrating its utility as a reactive intermediate in synthetic chemistry.
| Molecular weight | 106.14 |
|---|---|
| Linear formula | H2C=CHSO2CH3 |
| Assay | 98% |
| Boiling point | 115-117 °C/19 mmHg(lit.) |
| Density | 1.212 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.463(lit.) |
| Storage temperature | 2-8°C |
| Contains / stabiliser | 0.02% p-tert-butylphenol as stabilizer |
| Application | Methyl vinyl sulfone has been used:• as derivatization reagent in an improved method for detection of pseudouridine in nucleoside mixtures by capillary HPLC-mass spectrometry1• in preparation of methylsulfonylethyl cellulose via Michael addition to cotton fabric2• in Heck vinylation of aryl halides3 |


Hazard statements
- H302Harmful if swallowed
- H310Fatal in contact with skin
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P302IF ON SKIN
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >113 °C / >235.4 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 22-27-41 |
| Safety statements (S) | 26-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... LOC129293(129293) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl vinyl sulfone used for?
+
Methyl vinyl sulfone is used as a derivatization reagent in analytical chemistry for detecting pseudouridine, in material modification for preparing cellulose derivatives, and as a building block in organic synthesis, including Heck vinylation.
What is the CAS number and molecular formula for Methyl vinyl sulfone?
+
The CAS number for Methyl vinyl sulfone is 3680-02-2 and its molecular formula is C3H6O2S.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Methyl vinyl sulfone with a 98% assay. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards unless explicitly stated.
What are the main safety hazards associated with Methyl vinyl sulfone?
+
Methyl vinyl sulfone is classified as Danger. It is harmful if swallowed (H302), toxic in contact with skin (H310), and causes serious eye damage (H318). Appropriate personal protective equipment, including eye protection, gloves, and respiratory protection, is essential during handling.
How is Methyl vinyl sulfone packed, shipped, and exported?
+
Methyl vinyl sulfone is packed and shipped according to international regulations for hazardous materials. Tech Serve Solutions is experienced in global export.
How can I request a sample or quote for Methyl vinyl sulfone?
+
To request a sample or a quote for Methyl vinyl sulfone, please contact our sales department through the website or by telephone.
▶ Related products

3,4,5-Trimethoxybenzylamine
Organic Building Blocks

3,4-dihydroxyphenylacetone
Organic Building Blocks

3-Fluoro-4-methoxybenzonitrile
C8H6FNO
Organic Building Blocks
4-Ethyltoluene
C2H5C6H4CH3
Organic Building Blocks
Fluoroacetic acid
C2H3FO2
Organic Building Blocks
Methoxyacetaldehyde
C3H6O2
Organic Building Blocks
Methyl 4-acetamido-5-chloro-2-methoxybenzoate
Organic Building Blocks

Methyl 5-bromo-2-iodobenzoate
BrC6H3(I)CO2CH3
Organic Building Blocks


