Methyl (R)-(+)-3-bromo-2-methylpropionate
Methyl (R)-(+)-3-bromo-2-methylpropionate (CAS: 110556-33-7) is a chiral organic compound with the molecular formula BrCH₂CH(CH₃)CO₂CH₃ and a molecular weight of 181.03 g/mol. This ester is a valuable building block in asymmetric synthesis, offering a chiral centre for constructing complex molecules. It is primarily utilised in chemical synthesis for research and development purposes, contributing to the creation of novel compounds.
- IUPAC
- (+)-Methyl (R)-β-bromoisobutyrate
- Synonyms
- (+)-Methyl (R)-β-bromoisobutyrate

Chiral Building Block
Serves as a key intermediate in the stereoselective synthesis of enantiomerically pure compounds. Its defined stereochemistry allows for precise control in the construction of complex chiral molecules.
Asymmetric Synthesis
Employed in various asymmetric synthesis methodologies to introduce specific chiral fragments into target molecules. It is instrumental in the development of new synthetic routes for chiral pharmaceuticals and fine chemicals.
Organic Synthesis Intermediate
A versatile reagent for organic synthesis, facilitating the introduction of a functionalised chiral propionate moiety. It is used in multi-step syntheses to create diverse organic structures.
| Molecular weight | 181.03 |
|---|---|
| Linear formula | BrCH2CH(CH3)CO2CH3 |
| Assay | 97% |
| Boiling point | 85 °C/37 mmHg(lit.) |
| Density | 1.422 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.455(lit.) |
| Optical activity | [α]20/D +16°, neat |
| Optical purity | ee: 99% (GLC) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 73 °C / 163.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl (R)-(+)-3-bromo-2-methylpropionate used for?
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Methyl (R)-(+)-3-bromo-2-methylpropionate is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in organic synthesis for the development of complex molecules.
What are the CAS number and formula for Methyl (R)-(+)-3-bromo-2-methylpropionate?
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The CAS number is 110556-33-7, and the linear formula is BrCH₂CH(CH₃)CO₂CH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl (R)-(+)-3-bromo-2-methylpropionate with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for this chemical?
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This compound is a Warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Always wear eyeshields and appropriate gloves. Ensure adequate ventilation or use a suitable respirator, such as an ABEK type filter, in accordance with GHS hazard statements.
How is this product packed, shipped, and exported?
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Tech Serve Solutions adheres to stringent packaging standards for safe handling, transport, and export, ensuring product integrity and compliance with international regulations.
How can I request a sample or quote for this chemical?
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To request a sample or a quote, please contact our sales team via the website or directly via email, providing your specific requirements.
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