Methyl (3R)-(−)-3-(1-methylindol-3-yl)butanoate
Methyl (3R)-(−)-3-(1-methylindol-3-yl)butanoate (CAS: 460050-72-0) is a chiral indole derivative with the molecular formula C14H17NO2 and a molecular weight of 231.29 g/mol. This compound serves as a valuable building block in asymmetric synthesis and organic chemical research, particularly within the fields of heterocyclic chemistry and chiral compound development. Its specific stereochemistry makes it useful for constructing complex molecular architectures.

Chiral Building Block in Organic Synthesis
This compound is utilized as a stereochemically defined starting material or intermediate in the synthesis of complex organic molecules. Its indole core and chiral center are features exploited in constructing biologically active compounds and novel materials.
Asymmetric Synthesis Research
Researchers employ Methyl (3R)-(−)-3-(1-methylindol-3-yl)butanoate in developing new asymmetric synthetic methodologies. Its defined stereochemistry allows for the investigation and optimization of enantioselective reactions.
Heterocyclic Chemistry
As a substituted indole, this molecule finds application in studies and syntheses involving heterocyclic frameworks. Indole derivatives are prevalent in pharmaceuticals and natural products.
| Molecular weight | 231.29 |
|---|---|
| Empirical formula | C14H17NO2 |
| Assay | 98% |
| Optical activity | [α]20/D −7°, c = 1% in chloroform |
| Optical purity | ee: 97% (HPLC) |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41-42/43 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl (3R)-(−)-3-(1-methylindol-3-yl)butanoate used for?
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This compound is primarily used as a chiral building block and intermediate in organic synthesis, particularly in asymmetric synthesis and heterocyclic chemistry research.
What is the CAS number and formula for Methyl (3R)-(−)-3-(1-methylindol-3-yl)butanoate?
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The CAS number is 460050-72-0 and the empirical formula (Hill notation) is C14H17NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 98% and an optical purity of ee: 97% (HPLC). We do not represent this product as meeting pharmacopoeial standards such as USP, BP, or EP unless explicitly stated.
What are the safety and handling considerations?
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This compound is classified with Danger as a signal word, with hazards including H302 (Harmful if swallowed), H315 (Causes skin irritation), H317 (May cause an allergic skin reaction), H318 (Causes serious eye damage), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, is required. Handle in a well-ventilated area.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions offers this product in various pack sizes suitable for laboratory and research use. We are experienced global exporters, adhering to all necessary regulations for the safe and compliant shipment of chemicals worldwide.
How can I request a sample or a quote?
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Please contact our sales department directly via our website or by phone to request a sample or a quotation for Methyl (3R)-(−)-3-(1-methylindol-3-yl)butanoate.
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