Fmoc-Phe(2,4-Cl2)-OH
Fmoc-Phe(2,4-Cl2)-OH (CAS: 352351-62-3), a protected unnatural amino acid derivative, possesses the molecular formula C24H19Cl2NO4 and a molecular weight of 456.32. This compound is primarily utilised in chemical synthesis, particularly within peptide chemistry and chemical biology research. Its structure, featuring a phenylalanine core with dichlorination and Fmoc protection, makes it a valuable building block for constructing modified peptides and complex organic molecules.
- IUPAC
- Fmoc-2,4-dichloro-L-phenylalanine
- Synonyms
- Fmoc-2,4-dichloro-L-phenylalanineN-Fmoc-2,4-dichlorophenylalanine

Peptide Synthesis
Used as a protected unnatural amino acid building block in solid-phase or solution-phase peptide synthesis to introduce modified phenylalanine residues.
Chemical Biology Research
Incorporated into peptides or small molecules to probe biological systems or develop new chemical probes due to its unique structural features.
Drug Discovery
Serves as an intermediate in the synthesis of novel pharmaceutical compounds and peptidomimetics.
Organic Synthesis
Employed as a chiral building block in the construction of complex organic molecules and unnatural amino acid derivatives.
| Molecular weight | 456.32 |
|---|---|
| Empirical formula | C24H19Cl2NO4 |
| Assay | ≥98.0% (HPLC) |
| Storage temperature | 2-8°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Phe(2,4-Cl2)-OH used for?
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Fmoc-Phe(2,4-Cl2)-OH is used as a protected unnatural amino acid building block in peptide synthesis, chemical biology research, drug discovery, and general organic synthesis.
What is the CAS number and molecular formula for Fmoc-Phe(2,4-Cl2)-OH?
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The CAS number is 352351-62-3 and the molecular formula is C24H19Cl2NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Phe(2,4-Cl2)-OH with a purity of ≥98.0% (HPLC). We do not represent this product as USP, BP, or EP grade.
What are the safety and handling recommendations for Fmoc-Phe(2,4-Cl2)-OH?
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This compound is a Warning irritant, causing skin (H315), eye (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves, should be used. Ensure adequate ventilation and avoid inhalation of dust. If in eyes, rinse cautiously with water for several minutes (P305 + P351 + P338). Seek medical attention if irritation persists.
How is Fmoc-Phe(2,4-Cl2)-OH stored and shipped?
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Fmoc-Phe(2,4-Cl2)-OH should be stored at 2-8°C. Tech Serve Solutions can export this chemical globally, adhering to all necessary regulations.
How can I request a sample or quote for Fmoc-Phe(2,4-Cl2)-OH?
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You can request a sample or a formal quotation by contacting our sales department via the website or direct email, providing your specific requirements and shipping details.
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